Rapamycin can Inhibit the Development of Chlamydia pneumoniae, which Might Partly Contribute to the Prevention of In-stent Restenosis
Y Yan, S Silvennoinen-Kassinen, M Leinonen… - … drugs and therapy, 2010 - Springer
Background Rapamycin, an immunosuppressive and antiproliferative drug, is used to
prevent neointima formation to reduce the risk of in-stent restenosis with rapamycin eluting-
stents. Chronic infection of Chlamydia pneumoniae has been associated with
cardiovascular diseases, and could play an important role in the mechanism of restenosis.
We examined the effect of rapamycin on the growth of C. pneumoniae in cell cultures.
Methods HL cell monolayers were inoculated with C. pneumoniae CWL029 or C …
prevent neointima formation to reduce the risk of in-stent restenosis with rapamycin eluting-
stents. Chronic infection of Chlamydia pneumoniae has been associated with
cardiovascular diseases, and could play an important role in the mechanism of restenosis.
We examined the effect of rapamycin on the growth of C. pneumoniae in cell cultures.
Methods HL cell monolayers were inoculated with C. pneumoniae CWL029 or C …
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